The Cost of Adherence

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A recent analysis at the lab tells us that adherence is a still a big issue across a number of diseases.

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References

[i] Dezii CM. A retrospective study of persistence with single-pill combination therapy vs. concurrent two-pill therapy in patients with hypertension. Manag Care. 2000;9:2–6.

[ii] Dezii CM. Medication noncompliance: what is the problem? Manag Care. 2000 Sep;9(9 Suppl):7-12.

[iii] “Thinking Outside the Pillbox: Medication Adherence as a Priority for Health Care Reform,” David M. Cutler, Ph.D., and Wendy Everett, Sc.D., Engl J Med (362):1553-1555, April 29, 2010

[iv] Waalen J, Bruning AL, Peters MJ, Blau EM. A telephone-based intervention for increasing the use of osteoporosis medication: a randomized controlled trial. Am J Manag Care. 2009 Aug 1;15(8):e60-70.

[v] Dezii CM. Medication noncompliance: what is the problem? Manag Care. 2000 Sep;9(9 Suppl):7-12.

[vi] Morris AD, Brennan GM, Macdonald TM, Donnan PT. Population based adherence to prescribed medication in type 2 diabetes: a cause for concern. Diabetes. 2000;49(S1):abstract 307.

[vii] Dezii CM. Medication noncompliance: what is the problem? Manag Care. 2000 Sep;9(9 Suppl):7-12.

[viii] Ibid.

[ix] Ibid.

[x] Hou MY, et al “Using daily text-message reminders to improve adherence with oral contraceptives: A randomized controlled trial” Obstet Gynecol 2010; 116: 633–640.

[xi] Rand, CS, Wise, RA. Measuring adherence to asthma medication regimens. Am J Respir Crit Care Med 1994; 149:S69.

[xii] Thoonen, BP, Schermer, TR, Van Den Boom, G, et al. Self-management of asthma in general practice, asthma control and quality of life: a randomised controlled trial. Thorax 2003; 58:30.

[xiii] Dezii CM. Medication noncompliance: what is the problem? Manag Care. 2000 Sep;9(9 Suppl):7-12.

[xiv] New England Healthcare Institute. Thinking Outside the Pillbox: A Call for Demonstration Projects. Cambridge, MA. 2010.

[xv] Nordstrom BL, Friedman DS, Mozaffari E, Quigley HA, Walker AM. Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol. 2005;140:598-606.

[xvi] Reynolds NR, Testa MA, Su M, Chesney MA, Neidig JL, Frank I, Smith S, Ickovics J, Robbins GK; for the AIDS Clinical Trials Group 731 and 384 Teams. Telephone support to improve antiretroviral medication adherence: A multisite, randomized controlled trial. J Acquir Immune Defic Syndr. 2008 Jan 1;47(1):62-8.

[xvii] Cheever LW, Wu AW. Medication adherence among HIV infected patients: understanding the complex behavior of taking this complex therapy. Curr Infect Dis Rep. 1999;1:401–407.

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